benign giant lymph node hyperplasia
Definition: solitary masses of lymphoid tissue containing concentric perivascular aggregates of lymphocytes, occurring usually in the mediastinum or hilar region of young adults; similar changes have been reported outside the mediastinum and, if associated with interfollicular sheets of plasma cells, may progress to lymphoma or plasmacytoma.
Synonym(s): angiofollicular mediastinal lymph node hyperplasia, Castleman disease
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