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Bence Jones myeloma

Pronunciation: bents jonz

Definition: multiple myeloma in which the malignant plasma cells excrete only light chains of one type (either ? or ?); lytic bone lesions occur in about 60% of the cases, and light chains (Bence Jones protein) occur in the urine; amyloidosis and severe renal failure are more common than in multiple myeloma.

Synonym(s): L-chain disease, L-chain myeloma

[Henry Bence Jones]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.