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basement membrane

 

Definition: an amorphous extracellular layer closely applied to the basal surface of epithelium and also investing muscle cells, fat cells, and Schwann cells; thought to be a selective filter and to serve both structural and morphogenetic functions; it is composed of three successive layers (lamina lucida, lamina densa, and lamina fibroreticularis), a matrix of collagen (of which type IV is unique to the lamina densa of this membrane), and several glycoproteins.

Synonym(s): basement lamina, basilemma

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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