Definition: An infectious disease caused by a species of Babesia, transmitted by ticks. Animal hosts include cattle, sheep, deer, and dogs. Subclinical human infection may be common but symptomatic disease occurs only sporadically and in limited geographic distribution. Immunodeficient and asplenic people are at higher risk of infection. Clinical features of the disease include fever, chills, and hemolysis with hemoglobinuria and jaundice. Severe disease may be complicated by cardiac and renal failure, respiratory distress syndrome, and CNS involvement. As in animals, human morbidity and mortality increase with age.
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