Definition: an enzyme that catalyzes the reaction of ATP, water, and cobalamin to form orthophosphate, pyrophosphate, and adenosylcobalamin. Adenosylcobalamin is required by methylmalonyl-CoA mutase. A deficiency of ATP:cobalamin adenosyltransferase leads to methylmalonic acidemia.
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Examples: glitazone, GI cocktail, etc.