Definition: a kidney in which there is sclerosis of the arterioles, arteriolar nephrosclerosis resulting from long-standing benign hypertension. Such kidneys tend to be pale red-brown or relatively gray, moderately reduced in size, and firmer than normal organs; the capsular surfaces are uniformly finely granular. Most of the arterioles are thickened and hyalinized; there are, consequently, varying degrees of narrowing of the lumens, ischemia, and fibrosis in the interstitial tissue, leading to uniform contraction of the cortex.
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Examples: glitazone, GI cocktail, etc.