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Arnold-Chiari malformation

Pronunciation: ar'nold ke-ah're

Definition: malformed posterior fossa structures associated with caudad traction and displacement of the rhombencephalon as caused by tethering of the spinal cord; may be accompanied in some cases by spina bifida and associated anomalies such as meningomyelocele; usually multifactorial in inheritance.

Synonym(s): Arnold-Chiari deformity, Arnold-Chiari syndrome, cerebellomedullary malformation syndrome

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.