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Pronunciation: an′tē-tok′sin

Definition: Antibody formed in response to antigenic poisonous substances of biologic origin, such as bacterial exotoxins (those elaborated by Clostridium tetani or Corynebacterium diphtheriae), phytotoxins, and zootoxins; in general usage, antitoxin refers to whole, or globulin fraction of, serum from people or animals (usually horses) immunized by injections of the specific toxoid. Antitoxin neutralizes the pharmacologic effects of its specific toxin in vitro, and also in vivo if the toxin is not already fixed to the tissue cells.

[anti- + G. toxikon, poison]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.