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antibody-dependent cell-mediated cytotoxicity

 

Definition: a form of cell-mediated cytotoxicity mediated by natural killer cells with membrane bound Fc receptors. NK cells bind to antibody-coated microbes and the target cell may be killed through various modalities, perforin, reactive oxygen intermediates, cytokines.

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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