Definition: a complex fiber bundle curving around the medial edge of the internal capsule and connecting the anterior part of the temporal lobe (temporal cortex), amygdala, and olfactory cortex with the mediodorsal nucleus of the thalamus; it enters the thalamus as a component of the inferior thalamic peduncle, which also contains a major part of the fibers connecting the mediodorsal nucleus to the orbitofrontal cortex.
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Examples: glitazone, GI cocktail, etc.