Pronunciation: an′ī-on eks-chānj′
Definition: The process by which an anion in a mobile (liquid) phase exchanges with another anion previously bound to a solid, nonmobile, positively charged phase, the latter being an anion exchanger. For example, the process takes place when Cl− is exchanged for OH− in desalting. The reaction is Cl− (in solution) + (OH− on anion exchanger+) → (Cl− on anion exchanger) + OH− (in solution); in combination with the cation exchange, NaCl is removed from solution. Anion exchange may also be used chromatographically, to separate anions, and, medicinally, to remove an anion (Cl−) from gastric contents or bile acids in the intestine.
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Examples: glitazone, GI cocktail, etc.