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anaplastic lymphoma receptor tyrosine kinase


Definition: A gene located on the short arm of chromosome 2 in humans that encodes the anaplastic lymphoma kinase, also known as CD246, which functions as signal transduction tyrosine kinase. Mutations and gene rearrangements in this gene result in various neoplastic conditions.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.