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anaphylatoxin

Pronunciation: an′ă-fil-ă-tok′sin

Definition: Low molecular weight cleavage products (C3a, C4a, and C5a); generated by the activation of the complement cascade. They are proinflammatory; can cause permeability, smooth muscle contraction, and mask cell degranulation.

Synonym(s): anaphylotoxin

[anaphylaxis + toxin]

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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