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amyloid-precursor protein


Definition: a cell-surface receptor involved with neuritic growth, neuronal adhesion, and axonogenesis; cleavage of amyloid precursor protein by secretases generates beta-amyloid; abnormal synthesis of amyloid precursor protein leads to plaque formation in Alzheimer disease.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.