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aminoglycoside

Pronunciation: ă-mē′nō-glī′kō-sīd

Definition: Any one of a group of bacteriocidal antibiotics derived from species of Streptomyces or Micromonosporum and characterized by two or more amino sugars joined by a glycoside linkage to a central hexose; aminoglycosides act by causing misreading and inhibition of protein synthesis on bacterial ribosomes and are effective against aerobic gram-negative bacilli and Mycobacterium tuberculosis. Some commonly used aminoglycosides are streptomycin, neomycin, and gentamicin.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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