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Ames test

Pronunciation: amz

Definition: a screening test for possible carcinogens using strains of Salmonella typhimurium that are unable to synthesize histidine; if the test substance produces mutations that regain the ability to synthesize histidine, the substance is carcinogenic.

Synonym(s): Ames assay

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.