Skip to Content



Definition: a form of oxidation of fatty acids in which carbons are removed one at a time in the form of CO2; the a-carbon is first hydroxylated and then converted into a carbonyl; a deficiency of this pathway is associated with Refsum disease.

Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.