a local or general reaction of an organism following contact with a specific allergen to which it has been previously exposed and sensitized; immunologic mechanisms gives rise to inflammation or tissue damage. Allergic reactions are classified into four major types: type I, anaphylactic and IgE dependent; type II, cytotoxic; type III, immune-complex mediated; type IV, cell mediated (delayed).
Synonym(s): hypersensitivity reaction
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Examples: glitazone, GI cocktail, etc.