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aldosterone antagonist


Definition: an agent that opposes the action of the adrenal hormone aldosterone on renal tubular mineralocorticoid retention; these agents, spironolactone, are useful in treating the hypertension of primary hyperaldosteronism or the sodium retention of secondary hyperaldosteronism.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.