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aldose reductase


Definition: an oxidoreductase that reversibly converts aldoses to alditols (glucose to sorbitol) with NADPH as hydride donor, an important step in the metabolism of sorbitol and in the formation of diabetes-associated cataracts.

See Also: d-sorbitol-6-phosphate dehydrogenase

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.