Pronunciation: al′-a-nē-glī-oks′i-lāt a-mē′nō-tranz′fĕr-ās
Definition: An enzyme that reversibly catalyzes the transfer of an amino group of l-alanine to glyoxylate, thus producing pyruvate and glycine. An inherited disorder that results in an alteration of alanine-glyoxylate aminotransferase activity is associated with primary hyperoxaluria type I.
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Examples: glitazone, GI cocktail, etc.