Definition: the hormone of the anterior lobe of the hypophysis that governs the nutrition and growth of the adrenal cortex, stimulates it to functional activity, and shows extraadrenal adipokinetic activity; it is a polypeptide containing 39 amino acids, but exact structure varies from one species to another; sometimes prefixed by a to distinguish it from ß-corticotropin. The first 13 amino acids at the N-terminal region are identical to a-melanotropin.
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Examples: glitazone, GI cocktail, etc.