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adenylosuccinate lyase

Pronunciation: ad′e-nil-ō-sŭk′sin-āt lī′ās

Definition: an enzyme catalyzing the nonhydrolytic cleavage of adenylosuccinic acid producing AMP and fumarate and also of 4-(N-succinocarboxamido)-5-aminoimidazole nucleotide to yield fumarate and aminoimidazole carboxamide ribosyl-5-phosphate. Both are steps in purine nucleotide biosynthesis.

Synonym(s): adenylosuccinase, adenylylosuccinate lyase

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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