Pronunciation: ad′e-nil-ō-sŭk′sin-āt lī′ās
Definition: an enzyme catalyzing the nonhydrolytic cleavage of adenylosuccinic acid producing AMP and fumarate and also of 4-(N-succinocarboxamido)-5-aminoimidazole nucleotide to yield fumarate and aminoimidazole carboxamide ribosyl-5-phosphate. Both are steps in purine nucleotide biosynthesis.
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Examples: glitazone, GI cocktail, etc.