adenosine 3′,5′-cyclic monophosphate
Pronunciation: ă-den′ō-sēn sī′klik mo′nō-fos′fāt
An activator of phosphorylase kinase and an effector of other enzymes, formed in muscle from ATP by adenylate cyclase and broken down to 5′-AMP by a phosphodiesterase; the first compound referred to as a “second messenger.” It is a metabolic regulator. A related compound (2′,3′) is also known.
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Examples: glitazone, GI cocktail, etc.