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adenine phosphoribosyltransferase

 

Definition: an enzyme that catalyzes the reaction of adenine with 5-phospho-α-d-ribose 1-diphosphate (PRPP) to form AMP and pyrophosphate. An important step in purine salvage. A deficiency of this enzyme can lead to 2,8-dihydroxyadenine lithiasis.

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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