Skip to Content



Definition: A metalloprotease; its function is to cleave large von Willebrand multimers. Inhibition of ADAMS13 is associated with the hematologic disease thrombotic thrombocytopenic purpura. The name ADAMS13 comes from a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.