A genus of bacteria that has characteristics identical to those of the genus Mycoplasma, with the exception that the acholeplasmas do not require sterol for growth; saprophytic and parasitic species occur. Acholeplasma appears as a contaminant in tissue culture media that have been supplemented with animal sera. The type species is Acholeplasma laidlawii.
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Examples: glitazone, GI cocktail, etc.