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Medical Term:

acetyl-CoA carboxylase


a ligase that catalyzes the reaction of acetyl-CoA, CO2, H2O, and ATP, with covalently bound biotin to form malonyl-CoA, ADP, and Pi (or the reverse decarboxylase); N-carboxybiotin is an intermediate. A crucial enzyme in fatty acid synthesis.

© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.