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acetazolamide

Pronunciation: as′ĕ-tă-zol′ă-mīd

Definition: The heterocyclic sulfonamide 5-acetylamido-1,3,4-thiadiazole-2-sulfonamide, which inhibits the action of carbonic anhydrase in the kidney, increasing the urinary excretion of sodium, potassium, and bicarbonate, reducing excretion of ammonium, raising the pH of the urine, and lowering the pH of the blood; used in respiratory acidosis for diuresis and to stimulate respiratory drive, in glaucoma to reduce intraocular pressure, and in epilepsy.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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