Skip to Content

accessory molecules

 

Definition: surface receptors on immune cells, which participate in cell-cell interactions and modulate the immunologic outcome. For example, in T-cell recognition of B-cell presented–antigen, the primary interaction occurs through CD3-CD4 binding to MHC and antigen, but this interaction is amplified if concomitant accessory molecule binding also occurs, CD28 to B7.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

Hide