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ABC transporter proteins


Definition: a superfamily of carrier proteins that bind two highly conserved ATP-binding cassettes and function in transporting peptides, sugars, polysaccharides, and ions across the cell membrane. Mutations in the gene that codes for one of these ABC transporter proteins is believed to be responsible for cystic fibrosis.

[ATP-binding cassette]

See Also: cystic fibrosis, carrier protein

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.