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a1-antitrypsin deficiency panniculitis


Definition: multiple painful subcutaneous nodules occurring in patients with severe antitrypsin deficiency; biopsies show lobular panniculitis with neutrophils and foamy histiocytes. Some patients formerly diagnosed with Weber-Christian disease show this deficiency.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.