Definition: an enzyme that catalyzes the phosphorylation of d-fructose 6-phosphate by ATP (or other NTP) to fructose 1,6-bisphosphate and ADP (or other NDP); this enzyme catalyzes a step in glycolysis; it is inhibited by elevated levels of either ATP or citrate; a deficiency of this enzyme can lead to hemolytic anemia.
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Examples: glitazone, GI cocktail, etc.