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Pronunciation: fos'fo-fruk'to-ki'nas

Definition: an enzyme that catalyzes the phosphorylation of d-fructose 6-phosphate by ATP (or other NTP) to fructose 1,6-bisphosphate and ADP (or other NDP); this enzyme catalyzes a step in glycolysis; it is inhibited by elevated levels of either ATP or citrate; a deficiency of this enzyme can lead to hemolytic anemia.

Synonym(s): phosphohexokinase

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.