Definition: the pathway that ultimately converts 4-aminobutyrate to succinate; succinate is then converted to a-ketoglutarate, in the tricarboxylic acid cycle, which is then acted on by glutamate dehydrogenase; glutamate is then decarboxylated to reform 4-aminobutyrate; an important pathway for those cells that make this neuroactive molecule.
Synonym(s): GABA pathway
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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.