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3-oxoacid-CoA transferase

Pronunciation: ok'so-as'id trans'fer-as

Definition: An enzyme catalyzing the reversible conversion of acetoacetyl-CoA and succinate into succinyl-CoA and acetoacetate; malonyl-CoA can substitute for succinyl-CoA and a few other 3-oxo acids for the acetoacetate; an important step in order for the ketone bodies to serve as a fuel for extrahepatic tissues.

Synonym(s): 3-ketoacid-CoA transferase, acetoacetyl-succinic thiophorase

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.