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2-ketoadipic acid dehydrogenase complex

 

Definition: the multienzyme complex that reacts 2-ketoadipic acid with coenzyme A and NAD+ to produce glutaryl-CoA, CO2, and NADH + H+ in l-lysine and l-tryptophan catabolism; a deficiency of one of the proteins in this complex results in 2-ketoadipic acidemia.

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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