Definition: an enzyme of the Rapoport-Luebering shunt; it catalyzes the reversible interconversion of 1,3-bisphosphoglycerate to 2,3-bisphosphoglycerate; it also has a phosphatase activity, converting 2,3-bisphosphoglycerate to orthophosphate and 3-phosphoglycerate; a deficiency of 2,3-bisphosphoglycerate mutase can result in mild erythrocytosis.
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Examples: glitazone, GI cocktail, etc.