Generic Name: lucinactant (Intratracheal route)
Medically reviewed by Drugs.com. Last updated on Oct 29, 2019.
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
Therapeutic Class: Lung Surfactant
Uses for Surfaxin
Lucinactant injection is used to prevent respiratory distress syndrome (RDS) in premature infants at risk for RDS. RDS is a breathing or lung problem which is more common in premature infants because their lungs are not making enough surfactant. Surfactant is a liquid produced naturally in the lungs that helps an infant breathe air normally.
This medicine is to be given only by or under the direct supervision of a doctor.
Before using Surfaxin
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of lucinactant injection in premature infants.
No information is available on the relationship of age to the effects of lucinactant injection in geriatric patients.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Other medical problems
- Acute respiratory distress syndrome—Surfaxin® is not indicated for use in patients with this condition.
- Airway blockage or
- Bradycardia (slow heartbeat)—Use with caution. May make these conditions worse.
Proper use of Surfaxin
A doctor or other trained health professional will give your child this medicine in a hospital. This medicine is given directly into your child's lungs through his endotracheal (breathing) tube.
Precautions while using Surfaxin
It is very important that your child's doctor check your child's progress closely while receiving the medicine. This will allow the doctor to see if the medicine is working properly and to decide if your child should continue to receive it.
Surfaxin side effects
Check with your doctor or nurse immediately if any of the following side effects occur:
- Bluish lips or skin
- coughing up blood
- fast heartbeat
- fever or chills
- pale skin
- rapid, shallow breathing
- shortness of breath
- slow heartbeat
- troubled breathing
Incidence not known
- Blue or white in color
- heart may stop
- no oxygen to lungs
- patient unresponsive
- clay-colored stools
- dark urine
- decreased urine output
- fruit-like breath odor
- loss of appetite
- rapid, deep breathing
- swelling of the face, ankles, or hands
- unusual bleeding or bruising
- vomiting of blood
- yellow eyes or skin
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