Pms-Sodium Polystyrene Sulfonate (Oral)
Generic Name: sodium polystyrene sulfonate (Oral route)
SOE-dee-um pol-ee-STYE-reen SUL-foe-nate
Medically reviewed by Drugs.com. Last updated on Jun 22, 2019.
Commonly used brand name(s)
In the U.S.
- Pms-Sodium Polystyrene Sulfonate
Uses for Pms-Sodium Polystyrene Sulfonate
Sodium polystyrene sulfonate is used to treat high levels of potassium in the blood, also called hyperkalemia.
This medicine is available only with your doctor's prescription.
Before using Pms-Sodium Polystyrene Sulfonate
Appropriate studies have not been performed on the relationship of age to the effects of sodium polystyrene sulfonate in the pediatric population. However, pediatric-specific problems that would limit the usefulness of this medicine in children are not expected.
This medicine should be used with caution in newborn infants who have reduced or slow bowel movements. The oral form should not be given to newborn infants.
No information is available on the relationship of age to the effects of sodium polystyrene sulfonate in geriatric patients.
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
- Aluminum Carbonate, Basic
- Aluminum Hydroxide
- Aluminum Phosphate
- Calcium Carbonate
- Dihydroxyaluminum Aminoacetate
- Dihydroxyaluminum Sodium Carbonate
- Magnesium Carbonate
- Magnesium Hydroxide
- Magnesium Oxide
- Magnesium Trisilicate
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Interactions with food/tobacco/alcohol
Other medical problems
- Bowel blockage or
- Newborn infants who have slow bowel movements—Should not be used in patients with these conditions.
- Congestive heart failure, or
- Edema (fluid retention) or
- Heart rhythm problems (eg, arrhythmia, QT prolongation) or
- Hypertension (high blood pressure), severe or
- Hypocalcemia (low calcium in the blood) or
- Hypokalemia (low potassium in the blood)
- Hypomagnesemia (low magnesium in the blood)—Use with caution. May make these conditions worse.
- Hypovolemia (low blood volume) or
- Kidney disease—Use with caution. May cause side effects to become worse.
- Patients not having any bowel movements after a surgery
- Stomach or bowel problems (eg, bleeding, colitis, constipation, perforation), history of—Avoid use in patients with these conditions.
Proper use of Pms-Sodium Polystyrene Sulfonate
This section provides information on the proper use of a number of products that contain sodium polystyrene sulfonate. It may not be specific to Pms-Sodium Polystyrene Sulfonate. Please read with care.
Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.
This medicine comes as a liquid suspension and as a powder for suspension that is mixed with water or syrup. If you or your child are not able to swallow the liquid, the medicine can be given in the stomach using a special tube. Talk to your doctor if you have questions about this.
Mix the powder with 3 to 4 milliliters (mL) of water or syrup. Each dose of the powder must be mixed with a liquid right before you take it. Stir the powder mixture to dissolve the medicine. Do not store the liquid mixture to take later. Use it while in an upright position within 24 hours after it is mixed.
Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. Shake the bottle of medicine well just before each use.
Take this medicine at least 3 hours before or after taking other oral medicines. If your stomach takes too long to empty food (gastroparesis), take this medicine 6 hours before or after other oral medicines.
- For oral dosage form (powder, suspension):
- For treatment of hyperkalemia:
- Adults—15 grams (4 level teaspoons) one to four times a day.
- Children and infants—Dose is based on the potassium blood level and must be determined by your doctor.
- For treatment of hyperkalemia:
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Precautions while using Pms-Sodium Polystyrene Sulfonate
It is very important that your doctor check you or your child closely to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.
Hypokalemia (low potassium in the blood) may occur while you are using this medicine. Check with your doctor right away if you have the following symptoms: confusion, dry mouth, increased thirst, irregular heartbeat, irritability, muscle cramps, nausea or vomiting, or shortness of breath.
This medicine may cause a serious stomach or bowel problem, called intestinal necrosis. This is more likely to occur if you have a history of bowel disease, bowel surgery, low blood volume, kidney problems or if you take sorbitol together with this medicine. Tell your doctor right away if you or your child have severe constipation, severe stomach pain, bloody, black, or tarry stools, or vomit blood or a material that looks like coffee grounds.
Tell your doctor if you have unexplained weight gain or edema (fluid retention or body swelling) while using this medicine.
This medicine may cause lung or breathing problems (eg, bronchitis, bronchopneumonia) when you inhale its powder form. It may also increase your risk of having aspiration. Take this medicine in an upright position to prevent this. Talk to your doctor if you have questions.
If you are taking aluminum or magnesium-containing antacids or laxatives, talk to your doctor first before using them together with sodium polystyrene sulfonate. These medicines may keep sodium polystyrene sulfonate from working properly and may cause serious side effects.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Pms-Sodium Polystyrene Sulfonate side effects
Check with your doctor immediately if any of the following side effects occur:
- Bloody vomit
- chest pain
- cough producing mucus
- difficulty with breathing
- fever or chills
- severe stomach pain
- sore throat
- tightness in the chest
- troubled breathing
Incidence not known
- decrease in the amount of urine
- dry mouth
- increased thirst
- irregular heartbeat
- loss of appetite
- muscle cramps in the hands, arms, feet, legs, or face
- nausea or vomiting
- noisy, rattling breathing
- numbness and tingling around the mouth, fingertips, or feet
- severe constipation
- swelling of the fingers, hands, feet, or lower legs
- stomach cramps or pain
- troubled breathing at rest
- unusual tiredness or weakness
- weight gain
- weight loss
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
- fast, slow, or irregular heartbeat
- muscle spasms (tetany) or twitching
- pounding or rapid pulse
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More about sodium polystyrene sulfonate
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- During Pregnancy
- Dosage Information
- Drug Interactions
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- En Español
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- FDA Alerts (2)
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