Generic Name: chloramphenicol (Ophthalmic route)
Medically reviewed by Drugs.com. Last updated on Nov 16, 2019.
Commonly used brand name(s)
In the U.S.
- Isopto Fenicol
- Minims Chloramphenicol 0.5%
- Pentamycetin Ophthalmic Solution 0.25%
- Pentamycetin Ophthalmic Solution 0.5%
Chemical Class: Chloramphenicol (class)
Uses for Pentamycetin Ophthalmic Solution 0.25%
Chloramphenicol belongs to the family of medicines called antibiotics. Chloramphenicol ophthalmic preparations are used to treat infections of the eye. This medicine may be given alone or with other medicines that are taken by mouth for eye infections.
Chloramphenicol is available only with your doctor's prescription.
Before using Pentamycetin Ophthalmic Solution 0.25%
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of this medicine in children with use in other age groups.
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of this medicine in the elderly with use in other age groups.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Cholera Vaccine, Live
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Tetanus Toxoid
Interactions with food/tobacco/alcohol
Proper use of Pentamycetin Ophthalmic Solution 0.25%
This section provides information on the proper use of a number of products that contain chloramphenicol. It may not be specific to Pentamycetin Ophthalmic Solution 0.25%. Please read with care.
For patients using the eye drop form of chloramphenicol:
- Although the bottle may not be full, it contains exactly the amount of medicine your doctor ordered.
- To use:
- First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed and apply pressure to the inner corner of the eye with your finger for 1 or 2 minutes to allow the medicine to come into contact with the infection.
- If you think you did not get the drop of medicine into your eye properly, use another drop.
- To keep the medicine as germ-free as possible, do not touch the applicator tip or dropper to any surface (including the eye). Also, keep the container tightly closed.
To use the eye ointment form of chloramphenicol:
- First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Squeeze a thin strip of ointment into this space. A 1-cm (approximately 1/3-inch) strip of ointment is usually enough, unless you have been told by your doctor to use a different amount. Let go of the eyelid and gently close the eyes. Keep the eyes closed for 1 or 2 minutes to allow the medicine to come into contact with the infection.
- To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). After using chloramphenicol eye ointment, wipe the tip of the ointment tube with a clean tissue and keep the tube tightly closed.
To help clear up your infection completely, keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For eye infection:
- For ophthalmic ointment dosage form:
- Adults and children—Use every three hours.
- For ophthalmic solution (eye drops) dosage form:
- Adults and children—One drop every one to four hours.
- For ophthalmic ointment dosage form:
If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Precautions while using Pentamycetin Ophthalmic Solution 0.25%
If your symptoms do not improve within a few days, or if they become worse, check with your doctor.
Pentamycetin Ophthalmic Solution 0.25% side effects
Check with your doctor immediately if any of the following side effects occur:
Rare- may also occur weeks or months after you stop using this medicine
- Pale skin
- sore throat and fever
- unusual bleeding or bruising
- unusual tiredness or weakness
Check with your doctor as soon as possible if any of the following side effects occur:
- Itching, redness, skin rash, swelling, or other sign of irritation not present before use of this medicine
- Burning or stinging
After application, eye ointments may be expected to cause your vision to blur for a few minutes.
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