Medically reviewed on April 30, 2018.
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
Therapeutic Class: Antifungal
Chemical Class: Polyene
Uses For This Medicine
Natamycin belongs to the group of medicines called antifungals. It is used to treat some types of fungus infections of the eye.
Natamycin is available only with your doctor's prescription.
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For natamycin, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to natamycin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Studies on natamycin have been done only in adult patients, and there is no specific information comparing use of natamycin in children with use in other age groups.
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of natamycin in the elderly with use in other age groups, natamycin is not expected to cause different side effects or problems in older people than it does in younger adults.
|All Trimesters||C||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Proper Use of This Medicine
The bottle is only partially full to provide proper drop control.
- First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed for 1 or 2 minutes to allow the medicine to come into contact with the infection.
- If you think you did not get the drop of medicine into your eye properly, use another drop.
- To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.
To help clear up your eye infection completely, keep using natamycin for the full time of treatment, even if your condition has improved. Do not miss any doses.
The dose of natamycin will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of natamycin. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For fungus infection of the eye:
- For eye drops dosage form:
- Adults—Use one drop in the eye every four to six hours. For more serious infections, your doctor may tell you to use one drop in the eye every one or two hours for three or four days, then one drop six to eight times a day thereafter.
- Children—Use and dose must be determined by your doctor.
- For eye drops dosage form:
If you miss a dose of natamycin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Precautions While Using This Medicine
Your doctor should check your progress at regular visits. For some eye infections, these visits may be as often as several times a week.
If your symptoms do not improve within 7 to 10 days, or if they become worse, check with your doctor.
This Medicine Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- Eye irritation, redness, or swelling not present before use of natamycin
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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- Drug class: ophthalmic anti-infectives
Other brands: Natacyn