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Medications for Overactive Bladder

Other names: Bladder Hyperactivity; Chronic overactivity of the bladder; Detrusor hyperreflexia; Detrusor instability; Incontinence, Urge; Irritable Bladder; OAB; Spasmodic Bladder; Unstable Bladder; Urge Incontinence; Urinary Frequency

What is Overactive Bladder:  Overactive bladder is a problem with bladder storage function that causes a sudden urge to urinate. The urge may be difficult to suppress, and overactive bladder can lead to the involuntary loss of urine (incontinence).

Medications to treat Overactive Bladder

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
B & O Supprettes C 2 X 2 reviews
10

Generic name: belladonna / opium systemic

Drug class: narcotic analgesic combinations

For consumers: interactions, side effects

 
belladonna / opium C 2 X 7 reviews
9.0

Generic name: belladonna / opium systemic

Brand name:  B & O Supprettes

Drug class: narcotic analgesic combinations

For consumers: interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

 
Ditropan XL B N X 2 reviews
8.0

Generic name: oxybutynin systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Detrol C N X 14 reviews
7.0

Generic name: tolterodine systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Gelnique B N X 5 reviews
7.0

Generic name: oxybutynin systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Oxytrol B N X 44 reviews
7.0

Generic name: oxybutynin systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Sanctura C N X 15 reviews
7.0

Generic name: trospium systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Sanctura XR C N X 4 reviews
7.0

Generic name: trospium systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
trospium C N X 23 reviews
7.0

Generic name: trospium systemic

Brand names:  Sanctura XR, Sanctura

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
darifenacin C N 12 reviews
6.0

Generic name: darifenacin systemic

Brand name:  Enablex

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Detrol LA C N X 10 reviews
6.0

Generic name: tolterodine systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Enablex C N 12 reviews
6.0

Generic name: darifenacin systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
flavoxate B N X 2 reviews
6.0

Generic name: flavoxate systemic

Brand name:  Urispas

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Myrbetriq C N 88 reviews
6.0

Generic name: mirabegron systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
oxybutynin B N X 131 reviews
6.0

Generic name: oxybutynin systemic

Brand names:  Ditropan, Ditropan XL, Oxytrol, Anturol, Gelnique

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
tolterodine C N X 37 reviews
6.0

Generic name: tolterodine systemic

Brand names:  Detrol LA, Detrol

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Botox C N 88 reviews
5.0

Generic name: onabotulinumtoxinA systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
fesoterodine C N 37 reviews
5.0

Generic name: fesoterodine systemic

Brand name:  Toviaz

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Flomax Off Label B N X 10 reviews
5.0

Generic name: tamsulosin systemic

Drug class: antiadrenergic agents, peripherally acting

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
mirabegron C N 112 reviews
5.0

Generic name: mirabegron systemic

Brand name:  Myrbetriq

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

 
onabotulinumtoxinA C N 88 reviews
5.0

Generic name: onabotulinumtoxinA systemic

Brand name:  Botox

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
solifenacin C N 78 reviews
5.0

Generic name: solifenacin systemic

Brand name:  VESIcare

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
tamsulosin Off Label B N X 28 reviews
5.0

Generic name: tamsulosin systemic

Brand name:  Flomax

Drug class: antiadrenergic agents, peripherally acting

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Toviaz C N 37 reviews
5.0

Generic name: fesoterodine systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
VESIcare C N 72 reviews
5.0

Generic name: solifenacin systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
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Alternative treatments for Overactive Bladder

The following products are considered to be alternative treatments or natural remedies for Overactive Bladder. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Overactive Bladder.

Learn more about Overactive Bladder

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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