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Medications for Renal Cell Carcinoma

Other names: Adenocarcinoma of renal cells; Cancer, Hypernephroma; Cancer, Kidney; Cancer, Renal; Cancer, Renal Cell Carcinoma; Hypernephroma; Kidney Cancer; Renal Cancer

What is Renal Cell Carcinoma:  Renal cell carcinoma, a form of kidney cancer that involves cancerous changes in the cells of the renal tubule, is the most common type of kidney cancer in adults

Medications to treat Renal Cell Carcinoma

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
aldesleukin C N 1 review
10

Generic name: aldesleukin systemic

Brand name:  Proleukin

Drug class: miscellaneous antineoplastics, interleukins

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Nexavar D N 2 reviews
10

Generic name: sorafenib systemic

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Proleukin C N 1 review
10

Generic name: aldesleukin systemic

Drug class: miscellaneous antineoplastics, interleukins

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
sorafenib D N 2 reviews
10

Generic name: sorafenib systemic

Brand name:  Nexavar

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
temsirolimus D N 1 review
9.0

Generic name: temsirolimus systemic

Brand name:  Torisel

Drug class: mTOR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Torisel D N 1 review
9.0

Generic name: temsirolimus systemic

Drug class: mTOR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Avastin C N 1 review
8.0

Generic name: bevacizumab systemic

Drug class: VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
bevacizumab C N 1 review
8.0

Generic name: bevacizumab systemic

Brand name:  Avastin

Drug class: VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
pazopanib D N 46 reviews
8.0

Generic name: pazopanib systemic

Brand name:  Votrient

Drug class: VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Votrient D N 40 reviews
8.0

Generic name: pazopanib systemic

Drug class: VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Afinitor D N 1 review
7.0

Generic name: everolimus systemic

Drug class: mTOR inhibitors, selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
everolimus D N 1 review
7.0

Generic name: everolimus systemic

Brand name:  Afinitor

Drug class: mTOR inhibitors, selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
medroxyprogesterone Off Label X N 1 review
7.0

Generic name: medroxyprogesterone systemic

Drug class: hormones/antineoplastics, contraceptives, progestins

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
sunitinib D N 18 reviews
7.0

Generic name: sunitinib systemic

Brand name:  Sutent

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Sutent D N 16 reviews
7.0

Generic name: sunitinib systemic

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
axitinib D N Add review
6.0

Generic name: axitinib systemic

Brand name:  Inlyta

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Inlyta D N Add review
6.0

Generic name: axitinib systemic

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
nivolumab N 4 reviews
5.0

Generic name: nivolumab systemic

Brand name:  Opdivo

Drug class: Anti-PD-1 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Opdivo N 1 review
1.0

Generic name: nivolumab systemic

Drug class: Anti-PD-1 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Cabometyx D N Add review Rate

Generic name: cabozantinib systemic

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
cabozantinib D N Add review Rate

Generic name: cabozantinib systemic

Brand name:  Cabometyx

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
capecitabine Off Label D N Add review Rate

Generic name: capecitabine systemic

Drug class: antimetabolites

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
erlotinib Off Label D N Add review Rate

Generic name: erlotinib systemic

Drug class: EGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Off Label: Yes

 
lenvatinib N Add review Rate

Generic name: lenvatinib systemic

Brand name:  Lenvima

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Lenvima N Add review Rate

Generic name: lenvatinib systemic

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
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Topics under Renal Cell Carcinoma

Learn more about Renal Cell Carcinoma

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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