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Medications for Renal Cell Carcinoma

Other names: Adenocarcinoma of renal cells; Cancer, Hypernephroma; Cancer, Kidney; Cancer, Renal; Cancer, Renal Cell Carcinoma; Hypernephroma; Kidney Cancer; Renal Cancer

About Renal Cell Carcinoma:  Renal cell carcinoma, a form of kidney cancer that involves cancerous changes in the cells of the renal tubule, is the most common type of kidney cancer in adults

See also: sub-topics

Drugs Used to Treat Renal Cell Carcinoma

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Cabometyx D N Add review Rate

Generic name: cabozantinib systemic

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

cabozantinib D N Add review Rate

Generic name: cabozantinib systemic

Brand name:  Cabometyx

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

capecitabine Off Label D N Add review Rate

Generic name: capecitabine systemic

Drug class: antimetabolites

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

erlotinib Off Label D N Add review Rate

Generic name: erlotinib systemic

Drug class: EGFR inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Off Label: Yes

lenvatinib N Add review Rate

Generic name: lenvatinib systemic

Brand name:  Lenvima

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Lenvima N Add review Rate

Generic name: lenvatinib systemic

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Mvasi C N Add review Rate

Generic name: bevacizumab systemic

Drug class: VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

peginterferon alfa-2b Off Label C N Add review Rate

Generic name: peginterferon alfa-2b systemic

Drug class: antineoplastic interferons, antiviral interferons

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts

Off Label: Yes

Opdivo N 1 review
1.0

Generic name: nivolumab systemic

Drug class: Anti-PD-1 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

nivolumab N 4 reviews
5.0

Generic name: nivolumab systemic

Brand name:  Opdivo

Drug class: Anti-PD-1 monoclonal antibodies

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

axitinib D N Add review
6.0

Generic name: axitinib systemic

Brand name:  Inlyta

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Inlyta D N Add review
6.0

Generic name: axitinib systemic

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Afinitor D N 1 review
7.0

Generic name: everolimus systemic

Drug class: mTOR inhibitors, selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

everolimus D N 1 review
7.0

Generic name: everolimus systemic

Brand name:  Afinitor

Drug class: mTOR inhibitors, selective immunosuppressants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

medroxyprogesterone Off Label X N 1 review
7.0

Generic name: medroxyprogesterone systemic

Drug class: hormones/antineoplastics, contraceptives, progestins

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

sunitinib D N 21 reviews
7.0

Generic name: sunitinib systemic

Brand name:  Sutent

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Sutent D N 17 reviews
7.0

Generic name: sunitinib systemic

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Avastin C N 1 review
8.0

Generic name: bevacizumab systemic

Drug class: VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

bevacizumab C N 1 review
8.0

Generic name: bevacizumab systemic

Brand names:  Avastin, Mvasi

Drug class: VEGF/VEGFR inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

pazopanib D N 50 reviews
8.0

Generic name: pazopanib systemic

Brand name:  Votrient

Drug class: VEGF/VEGFR inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Votrient D N 44 reviews
8.0

Generic name: pazopanib systemic

Drug class: VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

temsirolimus D N 1 review
9.0

Generic name: temsirolimus systemic

Brand name:  Torisel

Drug class: mTOR inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Torisel D N 1 review
9.0

Generic name: temsirolimus systemic

Drug class: mTOR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

aldesleukin C N 1 review
10

Generic name: aldesleukin systemic

Brand name:  Proleukin

Drug class: miscellaneous antineoplastics, interleukins

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Nexavar D N 2 reviews
10

Generic name: sorafenib systemic

Drug class: multikinase inhibitors, VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

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Topics under Renal Cell Carcinoma

Learn more about Renal Cell Carcinoma

Micromedex® Care Notes

Symptoms and treatments

Mayo Clinic Reference

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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