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Medications for Pruritus

Other names: Itching; Itchy Skin

About Pruritus:  1. Itching, an unpleasant cutaneous sensation that provokes the desire to rub or scratch the skin to obtain relief.

2. Any of various conditions marked by itching, the specific site or type being indicated by a modifying term.

Drugs Used to Treat Pruritus

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
hydroxyzine N N X 29 reviews
7.0

Generic name: hydroxyzine systemic

Brand name:  Vistaril

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

pramoxine N N 5 reviews
9.0

Generic name: pramoxine topical

Brand names:  Sarna Sensitive, Pramox, Prax

Drug class: topical anesthetics

For consumers: dosage,

For professionals: AHFS DI Monograph

hydrocortisone C N 4 reviews
8.0

Generic name: hydrocortisone topical

Brand names:  Anucort-HC, Cortizone-10, Ala-Cort, Proctosol-HC, Proctozone HC, Ala-Scalp, Ala-Scalp HP, Anumed-HC, Anusol-HC, Anusol-HC Suppositories, Aquanil HC, Beta HC, Bioelements Immediate Comfort, Caldecort, Cetacort, Cortaid, Corticaine, Cortizone-5, Cortizone-10 Anal Itch Cream, Cotacort, Dermarest Plus Anti-Itch, Dermasorb HC, Dermtex HC, Gly-Cort, Gynecort Maximum Strength, Hytone, Instacort, Itch-X Lotion, Keratol HC, Lacticare-HC, Locoid, Locoid Lipocream, NuCort, Nutracort, Pandel, Pediaderm HC, Preparation H Anti-Itch Cream Hydrocortisone 1%, Procto-Kit 1%, Procto-Kit 2.5%, Procto-Med HC, Procto-Pak 1%, ProctoCare-HC, Proctocort, Proctocream-HC, Proctosert HC, Proctozone-H, Recort Plus, Rectacort-HC, Rectasol-HC, Sarnol-HC, Scalacort, Scalp-Cort, Texacort, Tucks Hydrocortisone Anti-Itch Ointment, U-Cort, Westcort …show all

Drug class: topical steroids

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

benzocaine C N 3 reviews
8.0

Generic name: benzocaine topical

Brand names:  Anacaine, Chiggerex, Dermoplast, Lanacane, Sting Relief …show all

Drug class: topical anesthetics

For consumers: dosage, interactions,

For professionals: AHFS DI Monograph, Prescribing Information

crotamiton C N 3 reviews
8.0

Generic name: crotamiton topical

Brand name:  Eurax

Drug class: topical anti-infectives

For consumers: dosage,

For professionals: A-Z Drug Facts, AHFS DI Monograph

gabapentin Off Label C N X 3 reviews
8.0

Generic name: gabapentin systemic

Drug class: gamma-aminobutyric acid analogs

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Sarna Sensitive N N 3 reviews
10

Generic name: pramoxine topical

Drug class: topical anesthetics

For consumers: dosage, side effects

calamine N N 2 reviews
9.0

Generic name: calamine topical

Brand name:  Calamine Plain

Drug class: miscellaneous topical agents

For consumers:

diphenhydramine / hydrocortisone N N 2 reviews
10

Generic name: diphenhydramine / hydrocortisone topical

Brand name:  HC-Derma-Pax

Drug class: miscellaneous topical agents

For consumers: dosage, interactions,

diphenhydramine B N X 2 reviews
7.0

Generic name: diphenhydramine systemic

Brand names:  Benadryl, Benadryl Allergy, Banophen, Benadryl Children's Allergy, Diphedryl, Allermax, Complete Allergy Relief, Dicopanol, Diphenhist, Dytuss, Q-Dryl, Quenalin, Scot-Tussin Allergy, Siladryl Allergy, Silphen Cough, Twilite, Valu-Dryl, Vanamine PD, Vicks QlearQuil Nighttime Allergy Relief …show all

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

doxepin B N X 2 reviews
9.0

Generic name: doxepin topical

Brand names:  Prudoxin, Zonalon

Drug class: topical antihistamines

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Eurax C N 2 reviews
7.0

Generic name: crotamiton topical

Drug class: topical anti-infectives

For consumers: dosage, side effects

For professionals: AHFS DI Monograph, Prescribing Information

HC-Derma-Pax N N 2 reviews
10

Generic name: diphenhydramine / hydrocortisone topical

Drug class: miscellaneous topical agents

For consumers: dosage, interactions, side effects

Lanacane C N 2 reviews
9.0

Generic name: benzocaine topical

Drug class: topical anesthetics

For consumers: dosage, interactions, side effects

Benadryl Allergy B N X 1 review
5.0

Generic name: diphenhydramine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

Cortizone-10 C N 1 review
10

Generic name: hydrocortisone topical

Drug class: topical steroids

For consumers: dosage, interactions, side effects

Prax N N 1 review
8.0

Generic name: pramoxine topical

Drug class: topical anesthetics

For consumers: dosage, side effects

Adazin B U Add review Rate

Generic name: benzocaine / capsaicin / lidocaine / methyl salicylate topical

For consumers: dosage,

For professionals: Prescribing Information

Ala-Cort C N Add review Rate

Generic name: hydrocortisone topical

Drug class: topical steroids

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Ala-Quin C N Add review Rate

Generic name: clioquinol / hydrocortisone topical

Drug class: topical steroids with anti-infectives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Ala-Scalp C N Add review Rate

Generic name: hydrocortisone topical

Drug class: topical steroids

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Ala-Scalp HP C N Add review Rate

Generic name: hydrocortisone topical

Drug class: topical steroids

For consumers: dosage, interactions, side effects

Allermax B N X Add review Rate

Generic name: diphenhydramine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

AmLactin B N Add review Rate

Generic name: ammonium lactate topical

Drug class: topical emollients

For consumers: dosage, side effects

ammonium lactate B N Add review
9.0

Generic name: ammonium lactate topical

Brand names:  AmLactin, Lac-Hydrin, Geri-Hydrolac, Kerasal AL, Laclotion …show all

Drug class: topical emollients

For consumers: dosage,

For professionals: Prescribing Information

Topics under Pruritus

Legend

Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Off Label This medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

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