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Medications for Multiple Sclerosis

Other names: MS

What is Multiple Sclerosis:  A disorder of the brain and spinal cord (central nervous system) caused by progressive damage to the outer covering of nerve cells (myelin). This results in decreased nerve functioning which can lead to a variety of symptoms.

Medications to treat Multiple Sclerosis

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
prednisone Rx C N Add review
6.0

Generic name: prednisone systemic

Drug class: glucocorticoids

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
interferon beta-1a Rx C N X 65 reviews
7.0

Generic name: interferon beta-1a systemic

Brand names:  Rebif, Avonex, Avonex Pen, Rebif Rebidose

Drug class: interferons

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts

 
dalfampridine Rx C N 52 reviews
8.0

Generic name: dalfampridine systemic

Brand name:  Ampyra

Drug class: miscellaneous central nervous system agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
fingolimod Rx C N 67 reviews
7.0

Generic name: fingolimod systemic

Brand name:  Gilenya

Drug class: selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
dexamethasone Rx C N 1 review
10

Generic name: dexamethasone systemic

Brand names:  Decadron, Dexamethasone Intensol, Baycadron, De-Sone LA, Dexacen-4, Dexasone, Dexasone LA, Dexpak Taperpak, Solurex, Solurex LA, Zema Pak

Drug class: glucocorticoids

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
dimethyl fumarate Rx C N 33 reviews
7.0

Generic name: dimethyl fumarate systemic

Brand name:  Tecfidera

Drug class: selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
glatiramer Rx B N 106 reviews
7.0

Generic name: glatiramer systemic

Brand names:  Copaxone, Glatopa

Drug class: other immunostimulants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
prednisolone Rx C N Add review
10

Generic name: prednisolone systemic

Brand names:  Prelone, Millipred, Veripred 20, Millipred DP, Orapred ODT, PediaPred

Drug class: glucocorticoids

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
teriflunomide Rx X N X 27 reviews
5.0

Generic name: teriflunomide systemic

Brand name:  Aubagio

Drug class: selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
interferon beta-1b Rx C N X 5 reviews
7.0

Generic name: interferon beta-1b systemic

Brand names:  Betaseron, Extavia

Drug class: interferons

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts

 
natalizumab Rx C N 81 reviews
7.0

Generic name: natalizumab systemic

Brand name:  Tysabri

Drug class: selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
valacyclovir Off Label Rx B N 2 reviews
9.0

Generic name: valacyclovir systemic

Drug class: purine nucleosides

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
azathioprine Rx D N 2 reviews
4.0

Generic name: azathioprine systemic

Brand names:  Imuran, Azasan

Drug class: antirheumatics, other immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
corticotropin Rx C N 7 reviews
6.0

Generic name: corticotropin systemic

Brand names:  Acthar, H.P. Acthar Gel

Drug class: corticotropin

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
cyclophosphamide Off Label Rx D N 3 reviews
6.0

Generic name: cyclophosphamide systemic

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
mitoxantrone Rx D N 1 review
7.0

Generic name: mitoxantrone systemic

Brand name:  Novantrone

Drug class: antibiotics/antineoplastics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
mycophenolate mofetil Off Label Rx D N 2 reviews
8.0

Generic name: mycophenolate mofetil systemic

Drug class: selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
alemtuzumab Rx C N 3 reviews
10

Generic name: alemtuzumab systemic

Brand name:  Lemtrada

Drug class: CD52 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
cladribine Off Label Rx D N Add review
9.0

Generic name: cladribine systemic

Drug class: antimetabolites

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
daclizumab Rx C N Add review Add

Generic name: daclizumab systemic

Brand name:  Zinbryta

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

 
ocrelizumab Rx U Add review Add

Generic name: ocrelizumab systemic

Brand name:  Ocrevus

Drug class: CD20 monoclonal antibodies

For consumers: interactions, side effects

For professionals: AHFS DI Monograph

 
peginterferon beta-1a Rx C N X 3 reviews
8.0

Generic name: peginterferon beta-1a systemic

Brand name:  Plegridy

Drug class: interferons

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 

Topics under Multiple Sclerosis

Learn more about Multiple Sclerosis

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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