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Medications for Melanoma, Metastatic

Metastatic melanoma is where the cancerous skin tumor has spread to parts of the body remote from the site of the primary tumor.

Drugs used to treat Melanoma, Metastatic

The following list of medications are in some way related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
encorafenib Rate Add review
Rx N
Generic name:
encorafenib systemic
Brand name:
Braftovi
Drug class:
multikinase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Proleukin Rate Add review
Rx C N
Generic name:
aldesleukin systemic
Drug class:
miscellaneous antineoplastics, interleukins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cobimetinib Rate Add review
Rx N
Generic name:
cobimetinib systemic
Brand name:
Cotellic
Drug class:
multikinase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
peginterferon alfa-2b Rate Add review
Rx C N
Generic name:
peginterferon alfa-2b systemic
Brand names:
PegIntron, Sylatron
Drug class:
antineoplastic interferons, antiviral interferons
For consumers:
dosage, interactions, side effects
talimogene laherparepvec Rate Add review
Rx N
Generic name:
talimogene laherparepvec systemic
Brand name:
Imlygic
Drug class:
miscellaneous antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
dacarbazine Rate Add review
Rx C N
Generic name:
dacarbazine systemic
Drug class:
alkylating agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Sylatron Rate Add review
Rx C N
Generic name:
peginterferon alfa-2b systemic
Drug class:
antineoplastic interferons, antiviral interferons
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
aldesleukin Rate Add review
Rx C N
Generic name:
aldesleukin systemic
Brand name:
Proleukin
Drug class:
miscellaneous antineoplastics, interleukins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
PegIntron Rate Add review
Rx C N
Generic name:
peginterferon alfa-2b systemic
Drug class:
antineoplastic interferons, antiviral interferons
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Braftovi Rate Add review
Rx N
Generic name:
encorafenib systemic
Drug class:
multikinase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Imlygic Rate Add review
Rx N
Generic name:
talimogene laherparepvec systemic
Drug class:
miscellaneous antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Cotellic Rate Add review
Rx N
Generic name:
cobimetinib systemic
Drug class:
multikinase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
isotretinoin Off-label Rate Add review
Rx X N X
Generic name:
isotretinoin systemic
Drug class:
miscellaneous antineoplastics, miscellaneous uncategorized agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
temozolomide Off-label 9.0 1 review for temozolomide to treat Melanoma, Metastatic
Rx D N
Generic name:
temozolomide systemic
Drug class:
alkylating agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
vemurafenib 6.3 4 reviews for vemurafenib to treat Melanoma, Metastatic
Rx D N
Generic name:
vemurafenib systemic
Brand name:
Zelboraf
Drug class:
multikinase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
binimetinib Rate Add review
Rx N
Generic name:
binimetinib systemic
Brand name:
Mektovi
Drug class:
multikinase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Zelboraf 6.3 4 reviews for Zelboraf to treat Melanoma, Metastatic
Rx D N
Generic name:
vemurafenib systemic
Drug class:
multikinase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Mektovi Rate Add review
Rx N
Generic name:
binimetinib systemic
Drug class:
multikinase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
dabrafenib 7.5 2 reviews for dabrafenib to treat Melanoma, Metastatic
Rx D N
Generic name:
dabrafenib systemic
Brand name:
Tafinlar
Drug class:
multikinase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
pembrolizumab 6.0 21 reviews for pembrolizumab to treat Melanoma, Metastatic
Rx D N
Generic name:
pembrolizumab systemic
Brand name:
Keytruda
Drug class:
anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
trametinib 9.5 2 reviews for trametinib to treat Melanoma, Metastatic
Rx D N
Generic name:
trametinib systemic
Brand name:
Mekinist
Drug class:
multikinase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Opdivo 6.8 11 reviews for Opdivo to treat Melanoma, Metastatic
Rx N
Generic name:
nivolumab systemic
Drug class:
anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
nivolumab 6.9 15 reviews for nivolumab to treat Melanoma, Metastatic
Rx N
Generic name:
nivolumab systemic
Brand name:
Opdivo
Drug class:
anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
ipilimumab 9.0 1 review for ipilimumab to treat Melanoma, Metastatic
Rx C N
Generic name:
ipilimumab systemic
Brand name:
Yervoy
Drug class:
anti-CTLA-4 monoclonal antibodies
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Keytruda 6.0 19 reviews for Keytruda to treat Melanoma, Metastatic
Rx D N
Generic name:
pembrolizumab systemic
Drug class:
anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

Frequently asked questions

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Learn more about Melanoma, Metastatic

Care guides

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.