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Medications for Period Pain (Dysmenorrhea)

What is Period Pain:  Difficult and painful menstruation.

Medications to treat Period Pain

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
ibuprofen C N X 13 reviews
7.0

Generic name: ibuprofen systemic

Brand names:  Advil, Advil Liqui-Gels, Motrin, IBU, Midol IB, Motrin IB, Ibu-8, IBU-200, Nuprin, Proprinal, A-G Profen, Actiprofen, Addaprin, Advil Children's, Genpril, Haltran, Ibu-4, Ibu-6, Ibu-Tab, Q-Profen

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
naproxen C N X 56 reviews
8.0

Generic name: naproxen systemic

Brand names:  Aleve, Naprosyn, Anaprox, Anaprox-DS, Midol Extended Relief, Naprelan, Flanax Pain Reliever, Aflaxen, All Day Pain Relief, EC-Naprosyn, All Day Relief

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
mefenamic acid C N X 34 reviews
6.0

Generic name: mefenamic acid systemic

Brand name:  Ponstel

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
diclofenac D N X 32 reviews
8.0

Generic name: diclofenac systemic

Brand names:  Cataflam, Voltaren, Voltaren-XR

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
ketoprofen C N X Add review
10

Generic name: ketoprofen systemic

Brand names:  Orudis, Oruvail, Orudis KT

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
celecoxib C N 2 reviews
5.0

Generic name: celecoxib systemic

Brand name:  Celebrex

Drug class: cox-2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
flurbiprofen C N X 1 review
8.0

Generic name: flurbiprofen systemic

Brand name:  Ansaid

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
meclofenamate N N X Add review Rate

Generic name: meclofenamate systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
trolamine salicylate N N Add review Rate

Generic name: trolamine salicylate topical

Brand names:  Arthricream, Asper-Flex, Myoflex

Drug class: topical rubefacient

For consumers: side effects

 
acetaminophen / caffeine N N X Add review Rate

Generic name: acetaminophen / caffeine systemic

Brand names:  Excedrin Tension Headache, Excedrin Quick Tab

Drug class: analgesic combinations

For consumers: dosage, interactions, side effects

 
acetaminophen / magnesium salicylate / pamabrom N N X Add review Rate

Generic name: acetaminophen / magnesium salicylate / pamabrom systemic

Brand name:  Pamprin Cramp Menstrual Pain Relief

Drug class: analgesic combinations

For consumers: interactions, side effects

 

Alternative treatments for Period Pain

The following products are considered to be alternative treatments or natural remedies for Period Pain. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Period Pain.

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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