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Medications for Chronic Lymphocytic Leukemia

The medications listed below are related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
acalabrutinib 9.3 14 reviews for acalabrutinib to treat Chronic Lymphocytic Leukemia
Rx N
Generic name:
acalabrutinib systemic
Brand name:
Calquence
Drug class:
BTK inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
alemtuzumab Rate Add review
Rx C N
Generic name:
alemtuzumab systemic
Brand name:
Campath
Drug class:
CD52 monoclonal antibodies
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Arzerra Rate Add review
Rx C N
Generic name:
ofatumumab systemic
Drug class:
CD20 monoclonal antibodies, selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Belrapzo Rate Add review
Rx D N
Generic name:
bendamustine systemic
Drug class:
alkylating agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
bendamustine 10 1 review for bendamustine to treat Chronic Lymphocytic Leukemia
Rx D N
Generic name:
bendamustine systemic
Brand names:
Treanda, Bendeka, Belrapzo, Vivimusta
Drug class:
alkylating agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Bendeka Rate Add review
Rx D N
Generic name:
bendamustine systemic
Drug class:
alkylating agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Breyanzi Rate Add review
Rx N
Generic name:
lisocabtagene maraleucel systemic
Drug class:
miscellaneous antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Brukinsa 9.3 6 reviews for Brukinsa to treat Chronic Lymphocytic Leukemia
Rx N
Generic name:
zanubrutinib systemic
Drug class:
BTK inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Calquence 9.3 13 reviews for Calquence to treat Chronic Lymphocytic Leukemia
Rx N
Generic name:
acalabrutinib systemic
Drug class:
BTK inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Campath Rate Add review
Rx C N
Generic name:
alemtuzumab systemic
Drug class:
CD52 monoclonal antibodies
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
chlorambucil 9.5 2 reviews for chlorambucil to treat Chronic Lymphocytic Leukemia
Rx D N
Generic name:
chlorambucil systemic
Brand name:
Leukeran
Drug class:
alkylating agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Copiktra Rate Add review
Rx N
Generic name:
duvelisib systemic
Drug class:
PI3K inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cyclophosphamide Rate Add review
Rx D N
Generic name:
cyclophosphamide systemic
Drug class:
alkylating agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
duvelisib Rate Add review
Rx N
Generic name:
duvelisib systemic
Brand name:
Copiktra
Drug class:
PI3K inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
fludarabine 6.0 1 review for fludarabine to treat Chronic Lymphocytic Leukemia
Rx D N
Generic name:
fludarabine systemic
Drug class:
antimetabolites
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Gammagard S/D Rate Add review
Rx C N
Generic name:
immune globulin intravenous systemic
Drug class:
immune globulins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Gazyva 0.0 1 review for Gazyva to treat Chronic Lymphocytic Leukemia
Rx C N
Generic name:
obinutuzumab systemic
Drug class:
CD20 monoclonal antibodies
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
hyaluronidase / rituximab Rate Add review
Rx N
Generic name:
hyaluronidase / rituximab systemic
Brand name:
Rituxan Hycela
Drug class:
CD20 monoclonal antibodies
For consumers:
dosage, interactions, side effects
ibrutinib 6.7 53 reviews for ibrutinib to treat Chronic Lymphocytic Leukemia
Rx D N
Generic name:
ibrutinib systemic
Brand name:
Imbruvica
Drug class:
BTK inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
idelalisib Rate Add review
Rx D N X
Generic name:
idelalisib systemic
Brand name:
Zydelig
Drug class:
PI3K inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Imbruvica 6.4 41 reviews for Imbruvica to treat Chronic Lymphocytic Leukemia
Rx D N
Generic name:
ibrutinib systemic
Drug class:
BTK inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
immune globulin intravenous Rate Add review
Rx C N
Generic name:
immune globulin intravenous systemic
Brand name:
Gammagard S/D
Drug class:
immune globulins
For consumers:
dosage, interactions, side effects
Jaypirca Rate Add review
Rx N
Generic name:
pirtobrutinib systemic
Drug class:
BTK inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Leukeran 9.5 2 reviews for Leukeran to treat Chronic Lymphocytic Leukemia
Rx D N
Generic name:
chlorambucil systemic
Drug class:
alkylating agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
lisocabtagene maraleucel Rate Add review
Rx N
Generic name:
lisocabtagene maraleucel systemic
Brand name:
Breyanzi
Drug class:
miscellaneous antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph

Frequently asked questions

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Learn more about Chronic Lymphocytic Leukemia

Care guides

Symptoms and treatments

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.