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Medications for Bipolar Disorder

The medications listed below are related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Abilify 5.6 345 reviews for Abilify to treat Bipolar Disorder
Rx C N X
Generic name:
aripiprazole systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Abilify Asimtufii Rate Add review
Rx C N X
Generic name:
aripiprazole systemic
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Abilify Maintena 6.0 23 reviews for Abilify Maintena to treat Bipolar Disorder
Rx C N X
Generic name:
aripiprazole systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Abilify MyCite Rate Add review
Rx C N X
Generic name:
aripiprazole systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
aripiprazole 5.6 437 reviews for aripiprazole to treat Bipolar Disorder
Rx C N X
Generic name:
aripiprazole systemic
Brand names:
Abilify, Abilify Maintena, Abilify Asimtufii, Abilify MyCite
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
armodafinil Off-label 9.3 15 reviews for armodafinil to treat Bipolar Disorder
Rx C 4
Generic name:
armodafinil systemic
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
asenapine 7.2 250 reviews for asenapine to treat Bipolar Disorder
Rx C N X
Generic name:
asenapine systemic
Brand name:
Saphris
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
bupropion Off-label 7.1 89 reviews for bupropion to treat Bipolar Disorder
Rx C N X
Generic name:
bupropion systemic
Drug class:
miscellaneous antidepressants, smoking cessation agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Caplyta 6.6 103 reviews for Caplyta to treat Bipolar Disorder
Rx N X
Generic name:
lumateperone systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
carbamazepine 7.0 109 reviews for carbamazepine to treat Bipolar Disorder
Rx D N X
Generic name:
carbamazepine systemic
Brand name:
Equetro
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
cariprazine 5.9 401 reviews for cariprazine to treat Bipolar Disorder
Rx N X
Generic name:
cariprazine systemic
Brand name:
Vraylar
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
citalopram Off-label 8.5 14 reviews for citalopram to treat Bipolar Disorder
Rx C N X
Generic name:
citalopram systemic
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
clonazepam Off-label 8.7 98 reviews for clonazepam to treat Bipolar Disorder
Rx D 4 X
Generic name:
clonazepam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
clonidine Off-label 8.1 9 reviews for clonidine to treat Bipolar Disorder
Rx C N X
Generic name:
clonidine systemic
Drug class:
antiadrenergic agents, centrally acting
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Depakote 6.2 185 reviews for Depakote to treat Bipolar Disorder
Rx D N X
Generic name:
divalproex sodium systemic
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Depakote ER 7.4 49 reviews for Depakote ER to treat Bipolar Disorder
Rx D N X
Generic name:
divalproex sodium systemic
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
desvenlafaxine Off-label 7.1 21 reviews for desvenlafaxine to treat Bipolar Disorder
Rx C N X
Generic name:
desvenlafaxine systemic
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
divalproex sodium 6.5 272 reviews for divalproex sodium to treat Bipolar Disorder
Rx D N X
Generic name:
divalproex sodium systemic
Brand names:
Depakote, Depakote ER
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
duloxetine Off-label 6.8 49 reviews for duloxetine to treat Bipolar Disorder
Rx C N X
Generic name:
duloxetine systemic
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Equetro 6.0 5 reviews for Equetro to treat Bipolar Disorder
Rx D N X
Generic name:
carbamazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
escitalopram Off-label 6.5 61 reviews for escitalopram to treat Bipolar Disorder
Rx C N X
Generic name:
escitalopram systemic
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Fanapt 5.5 2 reviews for Fanapt to treat Bipolar Disorder
Rx C N X
Generic name:
iloperidone systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
fluoxetine / olanzapine 7.7 48 reviews for fluoxetine / olanzapine to treat Bipolar Disorder
Rx C N X
Generic name:
fluoxetine / olanzapine systemic
Brand name:
Symbyax
Drug class:
psychotherapeutic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
gabapentin Off-label 8.4 140 reviews for gabapentin to treat Bipolar Disorder
Rx C N X
Generic name:
gabapentin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Geodon 5.5 242 reviews for Geodon to treat Bipolar Disorder
Rx C N X
Generic name:
ziprasidone systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

Frequently asked questions

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Topics under Bipolar Disorder

Learn more about Bipolar Disorder

Care guides

Symptoms and treatments

Medicine.com guides (external)

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.